Expression profiling of human idiopathic dilated cardiomyopathy
نویسندگان
چکیده
منابع مشابه
xpression profiling of human idiopathic dilated cardiomyopathy
Objective: To investigate the global changes accompanying human dilated cardiomyopathy (DCM) we performed a large-scale expression screen using myocardial biopsies from a group of DCM patients with moderate heart failure. By hierarchical clustering and functional annotation of the deregulated genes we examined extensive changes in the cellular and molecular processes associated to DCM. Methods:...
متن کاملIdiopathic Dilated Cardiomyopathy
Background Autoantibodies against the 81-adrenoceptor have been detected in the sera of patients with idiopathic dilated cardiomyopathy (DCM). The mechanisms by which these autoantibodies can alter normal receptor function are investigated, and the results are interpreted in the light of the beneficial effects of P1-blockade in some of these patients. Methods and Results Autoantibodies against ...
متن کاملIdiopathic dilated cardiomyopathy
I Yeoh CB, Hubaytar RT, Ford J, \'ylie RH. Trcatment of massive haemorrhage in pulmonary tuberculosis. j Thorauc Curdiovasc Surg 1967;54:50310. 2 Corey R, HIa KM. Major and massive haemoptysis: reassessment of conservative management. AmJ7Med Sct' 1987;294:301-9. 3 Crocco JA, Rooney JJ, Fankushen 1)S, DeBenedetto RJ, Lyons HA. Massive haemoptysis. Arch Intern. ed 1968;121:495-8. 4 Johtlston RN,...
متن کامل[Familial dilated cardiomyopathy in patients transplanted for idiopathic dilated cardiomyopathy].
OBJECTIVE To evaluate the prevalence, clinical features, and pattern of inheritance of familial dilated cardiomyopathy (DCM) in heart transplant patients. PATIENTS AND METHOD Patients with idiopathic DCM who had undergone heart transplantation were invited to participate. Patients with alcohol abuse were excluded. A clinical evaluation, 12-lead ECG, echocardiogram, blood tests, and DNA extrac...
متن کاملExpression of monocyte chemoattractant protein-1 in idiopathic dilated cardiomyopathy.
Immunological factors have been involved in the pathogenesis of dilated cardiomyopathy (DCM). The cytotoxic action of macrophages is one of the main factors causing cardiac myocyte damage. Monocyte chemoattractant protein-1 (MCP-1) is a major signal for the accumulation of monocytes/macrophages. We examined whether MCP-1 was expressed in the myocardium of DCM patients and whether the expression...
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ژورنال
عنوان ژورنال: Cardiovascular Research
سال: 2003
ISSN: 0008-6363
DOI: 10.1016/s0008-6363(03)00426-7